Scientific training encourages problem resolution grounded in knowledge, logic, and the systematic reduction in uncertainty. Whether conducting protocol feasibility or portfolio optimization, a disciplined, empirical approach to problem resolution reduces time to decision and reveals implicit assumptions for consideration. Albemarle Scientific Consulting can offer an external view on challenges from data interpretation to the differentiation strategy for a target product profile. A common outline for an engagement begins with a review of the applicable literature or client data, if available, followed by a didactic exchange to articulate objectives and assumptions. Next, the engagement transitions to phased working sessions and ends with documented conclusions and actionable recommendations.